In a series of possibly breakthrough research findings, it was found that Aspirin in low doses could protect the lungs and reduce the need to put patients in ventilators.
The pills are easily available to the common masses and has also been found to keep patients out of the Intensive Care Unit (ICU) and thereby, reducing chances of death.
Aspirin Dosage Can Reduce Risk Of Covid-19 Deaths
The research team from the George Washington University, who reported their findings in the journal of Anesthesia & Analgesia also reported that Aspirin use led to a reduction of 47% of in-hospital mortalities.
So far, Covid treatment drugs such as remdesivir could end up costing patients possibly thousands of dollars, Aspirin is an easily available over-the-counter drug.
Dr Jonathan Chow, assistant professor of Anesthesiology and critical care medicine at the George Washington School of Medicine and Health Sciences said that many Covid patients started forming blood clots throughout their bodies, which is when the doctors turned their attention towards Aspirin. The medication can prevent blood clots and is generally administered to heart attack patients.
Records of over 400 patients of different hospitals in the US between March and July 2020 were checked by the team who were administered a daily dose of aspirin from 24 hours of their arrival or during the 7 days prior to their admission, and they found that between March and July 2020, Aspirin was responsible for a 44% reduction in mechanical ventilation, 43% reduction in ICU cases and 47% reduction for in-hospital mortalities.
There are other studies as well that point in the same direction. As per a study published in PLOS One, a sample size of 30,000 US veterans infected by the Coronavirus was looked at. It was found that those already using aspirin had half mortality risk than those not prescribed for it.
However, Chow cautioned that his dream’s study looked into medical records, and did not practically test if patients would take aspirin or if it is a placebo effect.
Chow hailed the Recovery Trial in the UK which is investigating aspirin and Covid-19 in a gold standard randomized control trial that would settle the matter for good.
The Recovery Trials is a clinical trial to identify successful Covid-19 treatments. The trials are currently evaluating the following 3 treatments for Covid-19:
- Aspirin: Used to thin the blood.
- Regeneron’s Antibody Cocktail: Monoclonal antibodies directed against the Coronavirus.
- Baricitinib: An immuno-modulatory drug used in rheumatoid arthritis.
- Dimethyl Fumarate: An immuno-modulatory drug used for the treatment of psoriasis and multiple Sclerosis.
Studies have pointed towards 30%-70% of patients with Covid-19 and admitted in the ICU formed blood clots either in their legs or lungs.
Aspirin could be helpful as an anti-inflammatory drug to lessen the body’s inflammatory response against Covid-19 during phase 2 of the disease, said Dr. William Schaffner, an infectious disease expert at Vanderbilt University at Tennessee. However, Schaffner added, it cannot be used to prevent the virus.
So far, more than 29 million people across the US have been infected with Covid-19, resulting in 538,000 deaths so far. The vaccination campaign, which saw Pfizer and Moderna get emergency approval for Covid-19 double shot vaccines underwent early this year. So far, 113 million doses have been administered in the US, with an average of about 2.47 million doses per day.