CDC Says That Immunocompromised May Need 4th Dose

Nikki Attkisson | Last Updated : October 29, 2021

The difference between an additional dose of the Covid vaccine and a booster shot is that an additional shot is administered to people who have a moderately to severely compromised immune system.

The intention of this additional dose is to improve the person’s immune response to the initial vaccines.

When a person has completed their initial vaccine doses, a booster shot is administered.

CDC Says That Immunocompromised May Need 4th Dose

This is done with the intention of improving the protection offered by the vaccine which may have declined over time.

The CDC says that a 4th shot of the Covid vaccine may be required by people who have compromised immune systems.

The information about receiving an additional dose of the vaccine is limited. The evaluation of the safety, efficacy, and benefit of additional doses of the vaccine in individuals who are immunocompromised takes place every day.

CDC Says That Immunocompromised May Need 4th Dose

A very minute number of people have had severe allergic reactions to the vaccine, but this is very rare.

This reaction is known as anaphylaxis. This can occur after any vaccination.

Medicines are readily available with the providers of vaccines in order to treat the reaction.

After the Covid vaccine has been administered, people are asked to wait for 15-30 minutes in order to determine whether any immediate treatment is required if a severe allergic reaction is had.

There is a slight risk of developing thrombosis after receiving the J&J vaccine. It is rare and occurs in women.

7 out of every 1 million women who are vaccinated may have this reaction to the vaccine.

CNN reported that people should speak to their doctors in order to determine whether a 4th shot is required even though the agency did not provide an official recommendation in its updated guidelines.

A third shot was authorized by the CDC in August for certain people who are immunocompromised over the age of 18 who may possibly not get a complete immune response from the standard 2 doses.

Booster shots of all 3 available vaccines in the country have been approved by the FDA for specific people. This includes those who have compromised immune systems.

Small studies, according to the CDC have found that immunocompromised people who are fully vaccinated accounted for about 44% of breakthrough cases that led to hospitalization.

It was found by a study conducted at Johns Hopkins that immunocompromised people who are fully vaccinated are about 485 times more likely than most normal people to be hospitalized with Covid.

It has been shown by research that the antibody response to the vaccine is improved by a booster shot in certain immunocompromised people.

According to the CDC, people who are being treated for cancers of the blood, untreated HIV, organ transplant and stem cell recipients, and people who are required to take high doses of corticosteroids or other drugs that may suppress their immune system are included in the list for moderately to severely immunocompromised people.

It is estimated that around 9 million Americans, which translates to about 2% of the population, fall into this list.

A booster shot should be given to immunocompromised people who got the single-dose J&J vaccine, at least 2 months after the first dose.

The CDC, in its recommendations, said that a half-dose-sized shot that was authorized as a booster for Moderna’s vaccine should be given even if they had received a different vaccine as the first dose.

The CDC still recommends that people who have been vaccinated, if they are immunocompromised, should avoid places that have crowds or spaces that are poorly ventilated, in addition to always wearing a mask in indoor public spaces.


Nikki Attkisson

With over 15 years as a practicing journalist, Nikki Attkisson found herself at Powdersville Post now after working at several other publications. She is an award-winning journalist with an entrepreneurial spirit and worked as a journalist covering technology, innovation, environmental issues, politics, health etc. Nikki Attkisson has also worked on product development, content strategy, and editorial management for numerous media companies. She began her career at local news stations and worked as a reporter in national newspapers.

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